Organizing trust and confidence


We all want our pharmaceuticals and chemicals to be safe for human exposure. Therefore, we build regulatory frameworks which include methods to test for safety and efficacy or mode-of-action of our products. Many of these test methods were developed during the time the animal was considered to provide the best model to predict human safety and efficacy. Since then tremendous progress has been made in molecular, biological, physiological, chemical and toxicological knowledge and tools, including dedicated human systems. Join our dialogue on new ways of thinking and acting to organize trust and confidence for emerging human based research methods.

Organizing questions

How can we jointly organize trust and confidence in emerging in vitro and in silico tools? When is a tool good enough? How can we create room for innovation? What do you need to fully rely on the outcomes of animal-free tools or models? And finally: what can we, as participants in this session, do to create movement and affect change?

This session includes

  • short testimonials from diverse practices in chemical industry, food industry, pharma industry, funding organizations, researchers and regulators. 
  • several rounds of open dialogue in sub-groups on how to organize trust and confidence together.


If acceptance of animal free testing requires a complete paradigm shift, where do we begin to feel the outlines of a new paradigm?


Sue Gibbs, Amsterdam UMC
Anne Kienhuis, RIVM


Mister Lion