The TPI’s aim

As the initiators of the Transition Programme for Innovation without the use of animals, we want to put the Netherlands in the vanguard of animal-free innovation.


We are investing in knowledge development for the benefit of humans, animals and ecosystems. To achieve this goal, we must take a different approach to research methodology and design. How can we improve these aspects without the need for laboratory animals?

Animal-free innovation is a broad concept. Any new technique capable of providing a like-for-like replacement of an animal study is an animal-free innovation. Although in some research areas a lot can already be achieved without animal testing, no alternatives are yet in sight for other research areas. Even if alternative research models have been developed, they are often still little validated and recognised in the regulations.As this goal is often impossible, however, we must cast the net wider to include new methodology with regard to assessment, funding or data access.

First step

We are facing huge, pervasive transitions that often come at a considerable cost in terms of both time and money. Some of them require changes to international rules. As a result, it can be hard to predict when laboratory animals will hardly or no longer be required any more.

Accelerating the rate of innovation is an important first step. Such innovation includes developments in biotechnology and big data.

The Netherlands, Europe and the world

By thinking from a multidisciplinary perspective, we encourage researchers, risk assessors and other stakeholders to broaden their horizons. We are taking a coherent and international approach together with other Member States, partners and stakeholders, both at home and abroad.